What are Histamines and Heparin are released by?

I have been looking online for this and can't come up with an answer
Answers:    Short answer:
Heparin is produced in the liver and stored there and in other cell, such as mast cells.The levels contained by circulating blood are very low in normal conditions.... as for histamine .......
Histamine can end in inflammation directly as well as indirectly. Upon release of histamine by an antigen activated mast cell, permeability of vessel near the site is increased. Thus, blood fluids (including leukocytes, which participate in immune responses) enter the nouns causing swelling.
Histamine and Heparin are released from an antigen found in your liver. Red blood cells pass these through the body. Your liver acts as a "filter" for your body.

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